Human Plasma for Diagnostics — Bulk Supply | All Anticoagulants & Blood Types
SeamlessBio supplies human plasma for in vitro diagnostic (IVD) manufacturing, assay calibration, and kit development. Plasma is available as bulk material from certified EU and US donor centres — collected under standardised conditions, fully virally tested, and supplied with complete lot documentation.
All plasma is sourced and supplied on request. We do not maintain a fixed catalogue of small unit sizes — our core offering is bulk supply for manufacturers and kit developers. For specific donor configurations (blood type, anticoagulant, demographic, disease state), contact us directly. We can source virtually any human plasma specification from our network of certified collection centres.
Important: SeamlessBio supplies plasma as bulk material for B2B IVD manufacturing and research use only — not as individual clinical or patient samples. All orders are quotation-based. Minimum quantities and pricing depend on specification. On request, we can source any donor type, blood group, anticoagulant, or special demographic.
Available Plasma Types
| Plasma Type | Primary Application | Order |
|---|---|---|
| K2-EDTA Plasma Mixed blood types, mixed gender |
General IVD assay development, ELISA calibrators, immunoassay controls, haematology instrument calibration | Request bulk quote → |
| K2-EDTA Plasma, Type AB Universal donor type |
IVD assay development where blood group antibody interference must be excluded — ELISA, immunoturbidimetry, agglutination assays | Request bulk quote → |
| Li-Heparin Plasma Mixed blood types, mixed gender |
Clinical chemistry assay controls, point-of-care test development, electrolyte and metabolite assays. Li-heparin is the preferred anticoagulant for many clinical chemistry analysers. | Request bulk quote → |
| Citrate Plasma 3.2% sodium citrate |
Coagulation assay development, PT/aPTT controls, factor assay calibrators, haemostasis kit development | Request bulk quote → |
| Plasma — Custom Donor Type Any blood group, gender, demographic |
Special applications requiring defined donor demographics — Type O negative, male-only, female-only, age-specific cohorts, specific geographic origin. Available on request. | Specify requirements → |
| Plasma — Disease State / Special Condition On request |
Characterised plasma for assay validation using disease-specific analyte levels — contact us for availability of specific conditions | Specify requirements → |
Anticoagulant Selection Guide
| Anticoagulant | Mechanism | Best For | Avoid For |
|---|---|---|---|
| K2-EDTA | Chelates calcium — prevents coagulation cascade | Immunoassays, ELISA, molecular assays, haematology, general IVD matrix | Calcium or magnesium assays (EDTA chelates both), enzyme activity assays sensitive to metal chelation |
| Li-Heparin | Activates antithrombin — inhibits thrombin and factor Xa | Clinical chemistry (glucose, electrolytes, enzymes, proteins), point-of-care testing, many routine analyser methods | Coagulation assays, PCR (heparin inhibits polymerase), some immunoassays (heparin interference) |
| Sodium Citrate | Chelates calcium reversibly — coagulation preserved on recalcification | Coagulation assays (PT, aPTT, fibrinogen, factor assays), haemostasis assay development | General chemistry, immunoassays (citrate may affect analyte stability) |
Sourcing Capabilities — What We Can Source on Request
Our network of certified EU and US donor centres allows us to source plasma with virtually any specification. If you have a specific requirement not listed above, contact us with your specification. We will confirm availability and provide a quotation.
| Parameter | Available Options |
|---|---|
| Anticoagulant | K2-EDTA, K3-EDTA, Li-Heparin, Na-Heparin, Sodium Citrate (3.2%), ACD-A, ACD-B — specify on request |
| Blood type | Type A, B, AB, O — mixed or single type pools. Type AB male for universal donor applications. |
| Gender | Mixed, male-only, female-only — specify for hormone-sensitive applications |
| Origin | EU (Germany, France, other EU) | US — specify for regulatory documentation requirements |
| Processing | Fresh-frozen | Gamma irradiated (25–45 kGy) | Heat inactivated (56°C/30 min) — specify on request |
| Bulk volume | From 1 L upward — typical bulk orders 5–50 L. Larger volumes on request with lead time. |
| Aliquot size | Bulk (500 mL–1 L units) standard. Custom aliquot sizes on request for higher volumes. |
Quality & Documentation
| Parameter | Standard |
|---|---|
| Viral testing | HIV-1/2, HBsAg, HCV, HIV-1 RNA, HCV RNA, HBV DNA — FDA-approved methods, per donation |
| Sterile filtration | 0.2 µm — all lots |
| Collection standard | EU Directive 2002/98/EC — quality and safety of human blood and blood components |
| Donor centre certification | EU-licensed and/or FDA-registered collection centres |
| Origin | EU and/or US — traceable to collection centre |
| Documentation | CoA, CoO, MSDS — included with every bulk order |
| Extended documentation | Viral testing panel, donor centre certification, IVDR-compatible lot documentation — on request |
| Storage | −20 °C (fresh-frozen) | −80 °C for extended stability |
| Order basis | Quotation-based — contact us with specification, volume, and timeline |
Plasma vs Serum for Diagnostics — When to Use Which
| Parameter | Plasma | Serum |
|---|---|---|
| Clotting factors | ✅ Present (fibrinogen, factors V, VIII etc.) | ❌ Removed during clotting |
| Fibrinogen | ✅ Present | ❌ Absent |
| Anticoagulant present | ✅ Yes — EDTA, heparin or citrate | ❌ None |
| Coagulation assays | ✅ Citrate plasma required | ❌ Not suitable |
| Sample volume yield | ✅ Higher — plasma collected before clotting | Lower — serum yield ~60% of blood volume |
| Most common IVD matrix | ✅ Clinical chemistry, haematology, coagulation | ✅ Immunoassays, serology, endocrinology |
| Analyte stability | Generally better for labile proteins (fibrinogen, factors) | Better for some hormone assays (reduced cellular interference) |
Related Products
| Product | Application | Link |
|---|---|---|
| Human Serum for Immunoassays | ELISA controls, lateral flow development, serology matrix | View → |
| Human Serum Type AB Male | Universal donor serum — no anti-A/B antibodies for cell culture or immunoassays | View → |
| Human Serum Albumin (HSA) | Defined albumin source for IVD calibrators and assay diluents | View → |
| Auto-Immune Disease Controls | Characterised sera for ELISA kit validation and positive controls | View → |
Please include in your enquiry: anticoagulant, blood type, volume required, intended use, origin preference, and any special requirements. We will respond within 1 business day.
Contact: info@seamlessbio.de | +49 851 37932226