Tank Liners — Single-Use Liners for Stainless Steel Tanks | 50 L–5,000+ L | SeamlessBio
Tank Liners — Single-Use Liners for Stainless Steel & IBC Tanks | 50 L to 5,000+ L
Tank liners are single-use flexible bags designed to be inserted into existing stainless steel tanks, IBC containers, and portable totes. Instead of cleaning and validating the tank between batches, the disposable liner is replaced — eliminating cleaning validation, reducing turnaround time, and preventing product cross-contamination. Tank liners allow organisations to repurpose existing tank infrastructure for multi-product use without the regulatory burden of cleaning validation for each product.
SeamlessBio supplies tank liners manufactured from USP Class VI certified multilayer film, gamma sterilised, and available in standard sizes for common tank formats or fully customised to match your vessel dimensions and port layout. ISO 13485 certified manufacturing, Germany.
Key benefit: Tank liners convert your existing stainless steel tanks into single-use vessels — no new capital investment, no cleaning validation, no cross-contamination risk between products or batches. Ideal for multi-product facilities, contract manufacturing, and organisations scaling up from development to commercial production.
Key Applications
| Application | Details | Typical Volume |
|---|
| Bulk media storage | Store prepared cell culture media in stainless steel tanks with single-use liner — eliminate tank cleaning between media lots and media types | 200–5,000 L |
| Buffer preparation & hold | Prepare and hold large volumes of process buffers. Switch between buffer types without cleaning validation — change liner, change product. | 100–2,000 L |
| Bulk product storage | Store harvested cell culture fluid, concentrated protein, or purified bulk drug substance before final formulation — maintain sterility without stainless steel re-cleaning | 50–1,000 L |
| Freeze-thaw operations | Freeze bulk drug substance in tank liners at −20 °C or −80 °C. Single-use eliminates freeze-thaw stress on permanent vessel walls. | 50–500 L |
| Multi-product facilities (CMO/CDMO) | Single-use liners allow rapid product changeover in shared tank infrastructure — critical for contract manufacturers running multiple client products in the same facility | Any |
| IBC container lining | Line intermediate bulk containers (IBCs) for transport and storage of biopharmaceutical fluids — maintain sterility during logistics | 500–1,000 L |
| Vaccine bulk storage | Single-use liners for antigen bulk storage between manufacturing steps — prevents cross-contamination between vaccine strains in multi-product facilities | 200–2,000 L |
Why Tank Liners Instead of Tank Cleaning?
| Parameter | Traditional Tank Cleaning | Single-Use Tank Liner |
|---|
| Between-batch turnaround | Hours — cleaning, rinsing, validation sampling, release | ✅ Minutes — remove liner, insert new liner |
| Cleaning validation required | Yes — per product, per tank, documented | ✅ None — liner is single-use |
| Cross-contamination risk | Residual cleaning agent or product risk | ✅ Zero — fresh sterile liner every batch |
| Capital investment | CIP/SIP systems, validation equipment | ✅ Use existing tanks — no new investment |
| Water and utility consumption | High — rinse water, steam, energy for CIP/SIP | ✅ Minimal — liner disposal only |
| Multi-product flexibility | Dedicated tanks per product or full cleaning validation | ✅ One tank — unlimited products |
| Regulatory burden | 21 CFR Part 211.67, EU GMP Annex 15 cleaning validation | ✅ Eliminated for product contact surfaces |
Specifications
| Parameter | Specification |
|---|
| Volume range | 50 L, 100 L, 200 L, 500 L, 1,000 L, 2,000 L, 5,000 L | Larger volumes and custom sizes on request |
| Film material | USP Class VI certified multilayer polyethylene — optimised for biopharmaceutical contact |
| Sterilisation | Gamma irradiated — ≥25 kGy, validated per ISO 11137 |
| Temperature range | −80 °C to +60 °C (film rated) — suitable for freeze-thaw applications |
| Standard port configurations | Fill port, drain port, vent, sampling port — fully customisable |
| Connector options | Luer lock, TC fittings, MPX, custom sterile connectors |
| E&L testing | Extractables & leachables data available on request |
| Manufacturing | ISO 13485 certified facility, Germany |
| Documentation | CoA, CoO, gamma sterility certificate, USP Class VI compliance statement |
| GMP compliance | cGMP compatible — full validation documentation package available on request |
| Lead time | Standard sizes: 2–4 weeks | Custom dimensions: 6–10 weeks |
| Minimum order | 10 liners (standard) | Custom from 50 liners |
Customisation Options
| Option | Details |
|---|
| Custom dimensions | Liner sized exactly to your tank geometry — round, square, rectangular, conical bottom |
| Port layout | Number, position, and type of ports matched to your tank nozzle positions |
| Connector type | Tri-clamp (TC), Luer lock, MPX, AseptiQuik, or custom fittings matched to existing piping |
| Tubing length & type | C-Flex, silicone, or custom length specifications |
| Film grade | Standard or enhanced E&L profile for sensitive applications |
| Cryogenic grade | Film rated for −80 °C freeze-thaw — specify for bulk drug substance freezing |
| Custom printing | Company logo, batch codes, product codes on liner or outer packaging |
| Extended documentation | Validation data, regulatory support files, CoC — available for GMP submissions |
Single-Use Bioprocessing Portfolio
View all single-use products in the shop
Request a custom quote
Custom dimensions, bulk pricing, GMP documentation: info@seamlessbio.de | +49 851 37932226
