Bioprocess Tank Liners | 50-5000L | Single-Use Storage | SeamlessBio

Bioprocess Tank Liners for Large-Scale Storage

Single-use tank liners for stainless steel and plastic tanks. 50 liters to 5,000+ liters. Eliminate cleaning validation, reduce contamination risk. Made in Germany.

cGMP Compliant
USP Class VI
Gamma Sterilized
Made in Germany
Bioprocess Tank Liner in Container
Tank Liner System Diagram

What Are Bioprocess Tank Liners?

Bioprocess tank liners are flexible, single-use containment systems designed to fit inside stainless steel or plastic tanks, creating a sterile barrier between the tank surface and your biopharmaceutical products. These disposable liners eliminate the need for tank cleaning and sterilization, dramatically reducing validation requirements, turnaround time, and contamination risk.

Our tank liners are manufactured from USP Class VI certified polyethylene film, gamma sterilized to ensure sterility, and available in volumes ranging from 50 liters to 5,000+ liters. Each liner is custom-configured to fit your specific tank dimensions and process requirements, with multiple port options for filling, draining, sampling, and venting.

Why Choose Tank Liners Over Traditional Tank Cleaning?

  • Eliminate Cleaning Validation: No CIP/SIP required – save weeks of validation time
  • Reduce Contamination Risk: Fresh sterile liner for each batch
  • Faster Batch Turnaround: Switch between products in minutes
  • Lower Operating Costs: Reduce water, chemical, steam consumption by 70-90%
  • Enable Multi-Product Facilities: Use same tank for different products
  • Smaller Footprint: Eliminate dedicated cleaning areas
Tank Liner Sizes Comparison

Key Features & Benefits

Wide Volume Range

50L (R&D) to 5,000L+ (commercial). Custom sizes for your exact tank dimensions.

Universal Compatibility

Fits stainless steel, plastic containers, portable totes, IBCs. Fixed and portable configurations.

Custom Ports

Top fill, bottom drain, sampling, vent filters, temperature probes. MPC, tri-clamp, hose barbs.

Temperature Resistant

-20°C to +40°C range. Maintain product integrity across temperatures.

100% Tested

Every liner pressure tested. Burst strength >2 bar for safe filling and transport.

Transport Ready

Use in portable containers for safe transport. Reduce spillage and contamination risk.

Applications of Tank Liners

Bulk Storage Applications

  • Media Storage: Store prepared cell culture media at 2-8°C for up to 4 weeks
  • Buffer Storage: Hold buffers for chromatography, formulation, washing
  • Intermediate Product: Store harvested culture, clarified lysate, purified intermediates
  • Final Product: Hold bulk drug substance before fill/finish

Transport & Distribution

  • Inter-Facility Transport: Move materials between manufacturing sites
  • Contract Manufacturing: Ship to CMOs for fill/finish
  • Regional Distribution: Distribute to regional packaging facilities
  • Cold Chain: Maintain temperature during transport

Manufacturing Operations

  • Multi-Product Facilities: Switch products without cleaning
  • Campaign Manufacturing: Rapid changeover between campaigns
  • Flexible Capacity: Adjust volume based on batch size
  • Process Hold: Temporary storage during purification

Technical Specifications

Specification Details Standard
Material Polyethylene (PE) or EVOH USP Class VI
Film Thickness 300-600 µm ±10% tolerance
Burst Strength >2 bar (typical >3 bar) ASTM D751
Sterilization Gamma 25-50 kGy ISO 11137
SAL 10⁻⁶ ISO 11137
Temperature -20°C to +40°C Validated
E&L Data Available USP <661>, <1664>

Available Sizes

50-100L

Small Scale
R&D, pilot

200-500L

Medium Scale
Clinical mfg

1000L

Production
Commercial

2000-3000L

Large Scale
High volume

5000L+

Custom
Ultra-large

Frequently Asked Questions

What sizes are available?

50L to 5,000+ liters. Common: 200L, 500L, 1000L, 2000L, 3000L. Custom sizes with 50-100 unit minimum.

Will liners fit my tanks?

Custom-manufactured for cylindrical, rectangular, conical, dish bottom tanks. Provide dimensions for confirmation.

How do I install?

Insert folded liner, unfold, position ports, connect lines, fill slowly. Takes 15-30 minutes. Installation protocols provided.

Product recovery rate?

>99% recovery with proper drainage. Much better than traditional tanks (1-3% retention).

Lead time?

Standard: 4-6 weeks. Custom: 8-12 weeks including design and validation.

Ready to Simplify Storage?

Our team will help you select the right configuration and provide complete support.

Related Products

2D Bioprocess Bags

Smaller volumes (150mL-50L) for mixing, storage, transport.

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3D Bioprocess Bags

Bioreactor applications with optimized oxygen transfer.

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Container Systems

Portable containers (200-1000L) with integrated liners.

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All Products

Complete range of single-use bioprocessing solutions.

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SeamlessBio - Your Partner for Bioprocessing Solutions

Kohlbruck 20, 94036 Passau, Germany

Phone: +49 851 37932226 | Email: info@seamlessbio.de

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