CASY Cell Counter
Dye-free cell counting, viability determination and size distribution in under 60 seconds. GMP/GLP-compliant. Available through SeamlessBio for the DACH region.
Dye-free Measurement
No trypan blue, no consumables. Viability determined physically via ECE — reproducible results, free from staining artefacts.
GMP / GLP-compliant
NIST-traceable calibration beads. Optional 21 CFR Part 11 module. Full audit trail for regulated environments and QA documentation.
Results in <60 Seconds
Multiple measurements per minute. Direct LIMS export. Ideal for bioprocess monitoring and quality control.
Why the CASY Cell Counter?
Based on Electrical Cell Analysis (ECE) — the most accurate method for cell characterisation without chemical additives or staining steps.
100% Dye-free
No trypan blue, no reagents, no staining errors. Viability is determined by pure physical measurement — operator-independent every time.
Full Size Distribution
High-resolution volumetric analysis — aggregates, debris and viable cells separated automatically in real time.
GLP / GMP-compliant
NIST-traceable calibration. Optional 21 CFR Part 11 module with full audit trail for regulated manufacturing environments.
LIMS Integration
Direct data export to common LIMS platforms. One-click PDF reports with complete measurement history and audit trail.
Results in <60 Seconds
Multiple measurements per minute. High-throughput capable, ideal for at-line bioprocess monitoring and batch release QC.
Minimal Sample Prep
Direct measurement without elaborate preparation. Low sample volume and minimal running costs per measurement.
How it works
From sample to result in four simple steps — no staining, no incubation, no operator variation.
Aspirate sample
Place the capillary into your cell suspension — the instrument aspirates automatically.
ECE measurement
Each cell displaces electrolyte as it passes the aperture — size and count recorded at 1 MHz.
Automated analysis
Software separates viable cells, debris and aggregates in the size histogram automatically.
Export results
One-click PDF report or direct LIMS export — GMP-ready audit trail included.
Suitable for every cell type
From academic research to GMP-regulated manufacturing — optimised for the broadest range of cell lines and sample types.
CASY vs. conventional methods
Why trypan blue and haemocytometer methods no longer meet the demands of modern cell culture labs.
| Criterion | CASY Cell Counter | Trypan blue / Haemocytometer | Standard impedance counter |
|---|---|---|---|
| Dye-free measurement | ✔ Fully dye-free | ✗ Trypan blue required | ~ Reagent-dependent |
| Size distribution | ✔ Full histogram | ✗ Not possible | ~ Limited |
| GMP compliance | ✔ 21 CFR Part 11 | ✗ Not validatable | ~ Device-dependent |
| Reproducibility | ✔ ±1% CV | ✗ Operator-dependent | ~ ±5–10% CV |
| Measurement time | ✔ <60 seconds | ✗ 5–15 minutes | ~ 2–5 minutes |
| Debris discrimination | ✔ Automatic | ✗ Manual / error-prone | ~ Partial |
Frequently Asked Questions
Ready for more precise cell counting?
Speak with our specialist team — we'll demonstrate the CASY cell counter on your own cell types in a free remote demo. No commitment required.